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Topic: Substitution and Elimination at a Bridgehead  (Read 2888 times)

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Offline gingi85

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Substitution and Elimination at a Bridgehead
« on: December 15, 2007, 12:36:34 PM »
Will halides attached to bridghead positions react in any nuclephilic substituion or elimination reactions? It seems that all posibilites should be impossible, either because of steric hinderance, double-bonding at a bridgehead, or sp2 hybridization at the bridgehead.

Offline agrobert

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Re: Substitution and Elimination at a Bridgehead
« Reply #1 on: December 15, 2007, 09:03:17 PM »
This is a well studied topic.  I suggest you do some research.  Often studies are done with various tosylates as well.
In the realm of scientific observation, luck is only granted to those who are prepared. -Louis Pasteur

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