[Polleke]

Hallo all,

I was wondering if any chemist here could explain me if sterilizing PEG in an autoclave (20 minutes at 120°C) could damage the PEG structure and alter the characteristics of this PEG (polyethyleneglycerol).


cheers

[AWK]

PEG (polyethyleneglycerol)

Which one - polyethylene glycol or polyethyleneglycerol

PEG is relatively thermally stable
I guess polyethyleneglycerol is much less stable

[Polleke]

Polyethylene glycol !
PEG


I am sorry, my mistake, I wrote polyethyleneglycerol, but it has to be Polyethylene glycol

[eyke]

It depends on what molecular weight (MW) that u r using. usually the higher the MW the more stable it is to temperature.

Instead of heating it in oven, u can also use azeotropic distillation to dry the PEG.


...Cheers...

[Polleke]

It depends on what molecular weight (MW) that u r using. usually the higher the MW the more stable it is to temperature.

Instead of heating it in oven, u can also use azeotropic distillation to dry the PEG.


...Cheers...

I used a very high molecular weight: 9000


I hope I didnt change or break down the PEG by using an autoclave.

[eyke]

I think it should be OK.

Anyhow, u can check its structure to check is there any change or not after u heated it.

[Polleke]

true, I could do that, too bad that at the moment I do not have the proper recourses to check it.

But I suppose its still ok.

Thanks for you help eyke