[THC]

Hi

Is it possible to distinguish between two stereoisomers (diastereomere and enantiomere) with H/C-NMR?

And is it possible to distinguish between a staggered conformation and an eclipsed conformation (like here:http://en.wikipedia.org/wiki/Linear_alkane_conformation if the substituents were other thing than H)?

[playstyles]

I believe that enantiomers you cannot, diastereoisomers you can.
Cis and trans variations are generally included in diastereoisomers, and those can be
perceived as different in NMR.
Enantiomers, or mirror images have similar proton or carbon NMR as their connectivity is identical.

[dfodor]

It depends on the molecule. For example if it is a substituent on a benzene ring you have the chance to make a difference (shading effect of benzene ring).

[cumshyster]

Power...it all is a question of power...do you have enuf ? BWAAAAHAHAHA

[aldoxime_amine]

It depends on the molecule. For example if it is a substituent on a benzene ring you have the chance to make a difference (shading effect of benzene ring).

What does "shading effect of benzene ring" mean?