November 29, 2024, 01:38:21 PM
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Topic: Derivatization of cyclohexanone and 2-cyclohexen-1-one with Girard P hydrazine  (Read 2254 times)

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Offline potatohead44

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Hi there,

Just wondering if anyone had an idea why a reaction of Girard P hydrazine (pyridine with CCONHNH2 attached) would not react with cyclohexanone or 2-cyclohexen-1-one. Girard P hydrazine is a derivatising agent that replacing ketone groups. I am derivatising steroids and am successfully doing so by heating for 30mins at 70C and I am trying to find an internal standard.

Thanks all for your time,

potatohead44

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