[eer]

Hi,
I have to synthesize a pure enantiomer of an amphetamine derivative (R (-) MDMA), which has no psychoactive activity. However it is important to study its involvement in some neurotoxic lesions. To isolate it from the (+/-) MDMA it must be derivatized with 1(9-fluorenyl)ethyl need chloroformate solution but this reagent is very expensive. In sigma Aldrich the cost is 793 € for 10 ml and I need about 30-40 ml. Anyone have any idea if I can use any similar reagent more affordable? or how do I get the reagent at a reasonable price?
Thank you

[cpncoop]

If you're derivatizing an amino group, you could use the succinimidyl ester instead of the chloroformate solution.  Additionally, if you want to use the chloroformate solution, it shouldn't be necessary to use it in such a whopping excess.  5 eq in DCM should take care of it....

A cheaper reagent in general for derivitization would be dansyl chloride, which is used all over the place...