November 23, 2024, 04:05:33 AM
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Topic: Can someone help me draw the opening of this epoxide? Simple question.  (Read 2366 times)

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Offline toadesque

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This is the epoxide



I want to do a base-catalyzed opening. Doesn't really matter what base, maybe BuLi just as an example.

What will the mechanism look like if I wanted to show it in steps? I know a bond attached to the O will break and the base will attack but I'm not really sure how it's gonna look. And then it's followed by the addition of water.

Thanks

Offline Smrt guy

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SN2 attack at the primary carbon

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