[democanarchis]

I've been trying to find a reference for a generic sandmeyer reaction, eg. Ar-NH2 -> Ar-Cl using NaNO2, CuCl and HCl. Any recent papers are on ionic liquid/solid phase adaptations, and my institution doesn't have access to older papers. I want to try the reaction but can't find a paper that gives a basic experimental procedure. Can anyone point me to one? Thanks

[pacifyer]

In ionic liquid:
A. Hubbard, T. Okazaki, K. K. Laali, J. Org. Chem., 2008, 73, 316-319.

 

[408]

Cool to 0 the amine and acid.  Dropwise add nitrite with temperature control.  Add CuCl in HCl solution under same temperature control.  Wait a while.  Work up rxn.

[bromidewind]

OrgSyn.org most likely has a good basic reaction. I'd pull it up for you, but the site is down right now.

[AWK]

Vogel
Textbook of Practical Organic Chemistry

[democanarchis]

Vogel
Textbook of Practical Organic Chemistry

Thanks, found it in the library, just what I was looking for.