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Topic: chlorination of phenols  (Read 3683 times)

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Offline eunChae

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chlorination of phenols
« on: May 18, 2010, 01:45:04 PM »
     How can I chlorinate phenol and get 2,3,5-trichlorophenol? Bromination is relatively easy but chlorination is problematic as I know. Any suggestion for starting?
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Offline Grundalizer

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Re: chlorination of phenols
« Reply #1 on: May 18, 2010, 01:52:51 PM »
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Offline orgopete

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Re: chlorination of phenols
« Reply #2 on: May 18, 2010, 10:57:36 PM »
This looks like diazonium chemistry, so one route would be to start with a nitration.
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