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Topic: amino alcohol  (Read 2404 times)

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Offline jiangds05

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amino alcohol
« on: December 07, 2010, 05:03:18 PM »
what is the ratio of ester and amide when it reacts with acyl chloride? how should I enhance proportion of amide?
Thanks a lot :)
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Offline jiangds05

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Re: amino alcohol
« Reply #1 on: December 07, 2010, 10:01:33 PM »
Actually my question is how much alcohol would interfere with amine with electrophilic reagent?
would it be always necessary to protect alcohol when I want amine as reactive site with electrophilic reagent?


Quote from: jiangds05 on December 07, 2010, 05:03:18 PM
what is the ratio of ester and amide when it reacts with acyl chloride? how should I enhance proportion of amide?
Thanks a lot :)
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