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Topic: caffeine absorbtion and pH dependence  (Read 5103 times)

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Offline lespaul

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caffeine absorbtion and pH dependence
« on: February 03, 2011, 03:16:51 AM »
Does anyone know how pH affects the solubility of caffeine in the body (ie how fast it is absorbed in the small intestine).

Assuming that Coke (pH ~3) and coffee have the same concentration of caffeine (pH 5) - (I know they dont, but just follow me) - which beverage will be absorbed quicker into the bloodstream?

Im assuming the lower pH protonates the caffeine and ???

Offline JGK

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Re: caffeine absorbtion and pH dependence
« Reply #1 on: February 03, 2011, 02:36:00 PM »
It could be just a trick question:

The Coke and Coffee will end up in your stomach where they will combine with your stomach's acid secretions which will take them both to a uniform Ph before passing down the digestive system where the caffeine absorption will occur.
Experience is something you don't get until just after you need it.

Offline lespaul

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Re: caffeine absorbtion and pH dependence
« Reply #2 on: February 04, 2011, 11:16:16 PM »
Thanks JGK,  I didnt think about that.

Im also assuming that caffeine is absorbed - at least slightly - by your mouth and esophagus as it travels down.

I think I read somewhere that tea may be absorbed quicker - though dont quote me. Again, both have the same concentration (which they dont).

Just a curiosity I had, not an exam question.

Thanks

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