[malviyangr]

Hi,
i have synthesized 2,4,6-trimethylenebromo mesitylene from mesitylene. I have to use it for further reaction but it should be moisture free. Can i make it moisture free by dissolving it in DCM/chloroform and then adding anhydrous sodium sulphate to it. And then retaining back my compound. I want to ask whether this method is correct? Will there be any reaction of sodium sulphate and my compound? kindly tell sodium sulphate is unreactive to 2,4,6-trimethylenebromo mesitylene or not?
I'll be thankful for the reply.

[nox]

Sodium sulphate will not react with your compound, but the method you described is not likely to work.

I'm assuming your compound is a solid based on your description. A better way to do this is to put your compound into a desiccator, and then put the entire assembly under high vac (<10 mmHg) for a couple of days. If your compound does not sublime easily, I would probably heat it to say 50 degrees under high vac conditions overnight, that should pull out most of the residual moisture.

[malviyangr]

Hi,
i have synthesized 2,4,6-trimethylenebromo mesitylene from mesitylene. I have to use it for further reaction but it should be moisture free. Can i make it moisture free by dissolving it in DCM/chloroform and then adding anhydrous sodium sulphate to it. And then retaining back my compound. I want to ask whether this method is correct? Will there be any reaction of sodium sulphate and my compound? kindly tell sodium sulphate is unreactive to 2,4,6-trimethylenebromo mesitylene or not?
I'll be thankful for the reply.

[willug]

I had reasonable amount of success with that kind of method using molecular sieves... so that might be worth a try.