January 11, 2025, 05:50:02 PM
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Topic: Selectively reduce alkene in the presense of a ketone or aldehyde.  (Read 7782 times)

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Offline science123

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Can I use H2 , Pd (C) / EtOH for the first reaction?

For the second one, if we use Rosenmund Reduction (H2, Pd/BaSO4/S), would that reduce the nitro group also? Thanks

Offline discodermolide

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Re: Selectively reduce alkene in the presense of a ketone or aldehyde.
« Reply #1 on: April 11, 2011, 08:09:25 AM »


Can I use H2 , Pd (C) / EtOH for the first reaction?

For the second one, if we use Rosenmund Reduction (H2, Pd/BaSO4/S), would that reduce the nitro group also? Thanks


Look up transfer hydrogenation for No 1
And Rosenmund reduction for No 2
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Offline science123

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Re: Selectively reduce alkene in the presense of a ketone or aldehyde.
« Reply #2 on: April 14, 2011, 12:14:23 AM »
So does H2/Pd (C) /EtOH reduce carbonyls AND alkenes?

Does rosenmund reduction or LiAlH(otBu)3 affect the nitrogroup?

Offline discodermolide

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Re: Selectively reduce alkene in the presense of a ketone or aldehyde.
« Reply #3 on: April 14, 2011, 01:29:13 AM »
So does H2/Pd (C) /EtOH reduce carbonyls AND alkenes?

Does rosenmund reduction or LiAlH(otBu)3 affect the nitrogroup?

I suggested transfer hydrogenation for No 1 as you can reduce ketones with hydrogenation, but the conditions are forcing.
Rosenmund does not affect nitro nor will LiAl(OtBu)3.
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