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Preferential substitution on 2-dichloro-4-chloro-pentane
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Topic: Preferential substitution on 2-dichloro-4-chloro-pentane (Read 2105 times)
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scienceguy
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Preferential substitution on 2-dichloro-4-chloro-pentane
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January 02, 2012, 09:20:42 PM »
If you were reacting CH3-CCl2-CH2-CHCl-CH3 with a base (like hydroxide) aiming for a substitution reaction, which carbon would the base preferentially attack? The carbon with 2 chlorines or the carbon with 1 chlorine? Or would both get attacked?
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Organic_lover*
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Re: Preferential substitution on 2-dichloro-4-chloro-pentane
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January 21, 2012, 07:54:46 PM »
Well, I think that due the size of the chlorine atom the substitution is more probably to happen in the carbon with one chlorine.
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Preferential substitution on 2-dichloro-4-chloro-pentane