[Stundt]

Hi,

i want to synthesise Benzylamine  ?
so i have gone thru the preparations in the general org. text books but i need the procedure for doing the experiment
I hav evem gone thru Vogel's Practical Org .Chem


how can i get all the possible ways of synthesise benzylamine:
AS BENZYLAMINE WILL BE THE REAGENT FOR BY PROJECT

Regards
Stnd
                    HAVE A NICE DAY!

[discodermolide]

Hi,

i want to synthesise Benzylamine  ?
so i have gone thru the preparations in the general org. text books but i need the procedure for doing the experiment
I hav evem gone thru Vogel's Practical Org .Chem


how can i get all the possible ways of synthesise benzylamine:
AS BENZYLAMINE WILL BE THE REAGENT FOR BY PROJECT

Regards
Stnd
                    HAVE A NICE DAY!

By benzyl chloride, do a nucleophillic displacement of the chloride with azide. Then hydrogenolyse the benzyl azide.

[cakaro13]

Starting from benzene, you could do FC acylation, then reductive amination. The previous synthesis sounds a bit simpler though.

[discodermolide]

Starting from benzene, you could do FC acylation, then reductive amination. The previous synthesis sounds a bit simpler though.

A Friedel-Crafts acylation, with what?

[pacifyer]

Try a Gabriel synthesis... 

[Honclbrif]

Dude, just buy it. Its cheaper than pretty much any reasonable starting material.

[Stundt]

hmmmmmmm

I prefer buying the reagent
Actually running out of time so i prefer buying thanks  Honclbrif for the advice

I would hav prepared from benzyl chloride but therez a problem with that it forms byproducts like dibenzyl chloride and tertiary products




Thanks for the replies
                         

[discodermolide]

hmmmmmmm

I prefer buying the reagent
Actually running out of time so i prefer buying thanks  Honclbrif for the advice

I would hav prepared from benzyl chloride but therez a problem with that it forms byproducts like dibenzyl chloride and tertiary products




Thanks for the replies
                         

No it doesn't, you get a very clean product with this azide reaction. I've done it many times on very large scale.