[ONUR GÜMÜŞ]

how can i do this reaction,   ? thanks...

[fledarmus]

Do you mean how would you carry it out in the lab, or what is the mechanism for the reaction occurring on paper?

[ONUR GÜMÜŞ]

how can i do this reaction in lab?

[sjb]

how can i do this reaction in lab?

Perhaps search for something like enones and thiourea or similar? (e.g. http://dx.doi.org/10.1080/10426500108040582 )

[fledarmus]

Have you done any searching at all for this reaction? I get 195 hits using SciFinder. The first few seem to use KOH in EtOH at reflux.

What tools do you have available for searching reactions?

[ONUR GÜMÜŞ]

usually I am using the web of science and science direct. I used these methods in the search engines.. I found the article in science direct which is in DMF at reflux.

[fledarmus]

That may depend on what your R group is. Here is a reference for both R groups being simply phenyl rings:

Preparation of heterocycles by the reaction of diaza binucleophiles with chalcones: influence of the substituent on position 2;  Simon, Dominique et al, Journal of Heterocyclic Chemistry, 22(6), 1551-7; 1985.

The reaction doesn't seem to work nearly as well if the R groups are alkyl groups - lower yields in general and more forcing conditions.

[AWK]

http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv5p0703

[ONUR GÜMÜŞ]

Thank you very much everyone.
Now I've started a method of KOH and EtOH.
I hope it happens