[shalikadm]

I know that we can attach -COR to benzene ,toluene ,phenol ,ammonia ,Primary amine ,Secondary amine ,grignard reagent ,H₂O ,NaOH ,aniline ,alcohols with RCOCl/anhidrous AlCl₃

We can even use acid anhydride to do the same thing to benzene,phenol,aniline,alcohol.

1.Can we use acid anhydride to attach -COR to the all other compounds listed in bold.If not tell me which goes with acid anhydride ?
2.Do we need anhydrous AlCl₃ when we are using acid anhydride?
3.can we call any attaching -COR as "acylation " (even to water and NaOH)
4.Is "friedel craft acylation" given for acylation an aromatic ring ?
Then which are from the above boldtype list
5.In alkylation of nitrobenzene do we need to heat the solution unlike in benzene/toluene alkylation ?
6.Can we have something like AlBr₃ instead of AlCl₃ in the process. If we can, do we have to use RCOBr instead of RCOCl ?

[Hunter2]

1. yes

2. no, but it helps catalytic

3. H₂O, NaOH gives hydrolysis

4. Yes

5. Recipes can be found in organic cook books, I guess you have to heat, yes

6. AlX₃ X = Cl, Br, I can be used. Not necessary to have RCO-X. The Chloride is fine. Also FeCl₃, SnCl₂, BF₃ and other Lewis acids.

[shalikadm]

2. no, but it helps catalytic

then acid anhydride works without AlCl₃ ?
is it necessary to have AlCl₃ for RCOCl in every above reaction or is it necessary for some of above reactions ?(tell me which they are)

3. H2O, NaOH gives hydrolysis

then we can't call them ''acylation'' ?(H₂O+RCOCl & NaOH+RCOCl)

4. Yes

Which are they ?
Does o-acylation of phenol include in "friedel craft acylation" ?

5. Recipes can be found in organic cook books, I guess you have to heat, yes

What are the other reactions listed above which need heat ?

[Hunter2]

2. AlCl₃ is necessary on aromatic systems like benzene and derivates. All hetero atoms will be attacked directly.
Acid anhydride works Hydronium catalysted.

3. correct

4.which can it be in the list? no

5. Heat willacelarate reactions. So all of them will go faster with heat.

By the way some homework you should do also by yourself.

[shalikadm]

Thanks a lot !

4.which can it be in the list? no
By the way some homework you should do also by yourself.

Any way this is not homework..I was trying to get a full understanding about what I'm learning