[ufopolicia]

Hey everyone I just have a question regarding hydrochloride and tartrate salts. In a reaction scheme I am trying to follow, it says I need a hydrochloride salt, but if the same chemical as a tartrate salt is available would I be able to use it in place of the hydrochloride salt? Or would I have to use the hydrochloride salt. Or does it depend on what the chemical is? Thanks guys!

[discodermolide]

Hey everyone I just have a question regarding hydrochloride and tartrate salts. In a reaction scheme I am trying to follow, it says I need a hydrochloride salt, but if the same chemical as a tartrate salt is available would I be able to use it in place of the hydrochloride salt? Or would I have to use the hydrochloride salt. Or does it depend on what the chemical is? Thanks guys!

In principle yes, it sounds like you have an amine that you ned to liberate before reaction. This is done by using a base like sodium hydroxide or sodium carbonate. You get the inert sodium chloride as a by-product in the first case and the second gives sodium tartrate. Sodium tartrate may interfere with the next reaction. So stick with the hydrochloride.