November 28, 2024, 03:27:32 AM
Forum Rules: Read This Before Posting


« previous next »
Pages: [1]   Go Down

Topic: P-2 Nickel Reduction  (Read 1975 times)

0 Members and 1 Guest are viewing this topic.

Offline AlphaScent

  • Full Member
  • ****
  • Posts: 644
  • Mole Snacks: +24/-7
  • Gender: Male
P-2 Nickel Reduction
« on: August 17, 2012, 02:36:10 PM »
I just did a standard P-2 nickel reduction of an internal alkyne.  I got 74% yield.  Does that seem low to anyone who has done one? 
Logged
If you're not part of the solution, then you're part of the precipitate

Offline discodermolide

  • Chemist
  • Sr. Member
  • *
  • Posts: 5038
  • Mole Snacks: +405/-70
  • Gender: Male
    • My research history
Re: P-2 Nickel Reduction
« Reply #1 on: August 17, 2012, 02:39:14 PM »
Quote from: AlphaScent on August 17, 2012, 02:36:10 PM
I just did a standard P-2 nickel reduction of an internal alkyne.  I got 74% yield.  Does that seem low to anyone who has done one? 

Maybe a bit low but not bad for a first shot. Perhaps some over reduction?
Logged
Development Chemists do it on Scale, Research Chemists just do it!
My Research History

Offline AlphaScent

  • Full Member
  • ****
  • Posts: 644
  • Mole Snacks: +24/-7
  • Gender: Male
Re: P-2 Nickel Reduction
« Reply #2 on: August 17, 2012, 03:18:12 PM »
No over reduction by GC.  Did not take an NMR though.  I think I can do better, next time.  Ill let you know.  Thanks Dan.
Logged
If you're not part of the solution, then you're part of the precipitate
Pages: [1]   Go Up
« previous next »
Sponsored Links