Atoms in crystals produce diffraction patterns because the x-ray light scattered from the atoms in one unit cell constructively interferes with the light scattered from all the other unit cells in the crystal. If an atom displays heterogeneity in its position (i.e. it is in different places in different unit cells), the light scattered from these atoms will not constructively interfere as well. Therefore, the light that would have come from this atom were it well positioned is lessened, and this atom contributes less signal to the intensity of the spots in the diffraction pattern.