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Topic: derivatization for GC-MS  (Read 7545 times)

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Offline GSR

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derivatization for GC-MS
« on: December 28, 2005, 08:33:35 AM »
Hi,

can anybody  give detailed information on derivatizing a natural product sample with diazomethane, and purification procedures for side products etc... which I need for the GC-MS analysis.

thanks in advance

GSR
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Offline jwesterway

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Re:derivatization for GC-MS
« Reply #1 on: January 18, 2006, 08:09:09 AM »
This is highly dependant on the sample, diaztisation is used as a derivitising agent for many functional groups to increase their volitility and/or stability under GC analysis. What is the sample comprised of?

-josh
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Offline Mitch

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Re:derivatization for GC-MS
« Reply #2 on: January 18, 2006, 12:26:34 PM »
Whats the Molecular Weight? Why can't you use GC-MS?
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