Eating fugu just strikes me as, well, an extremely dangerous thing to do, for more or less no gain whatsoever, apart from perhaps a meal, if you consider that TTX can quite easily prove lethal at a dose of 0.5-1mg, for the sake of a quick snack on some sushi, however carefully prepared I don't think its worth the risk taken, it doesn't take much of a slip by the chef for it to become one's last meal.
Whereas with any recreational/spiritually used drug I can think of, there is quite a massively larger degree of safety, save only for etorphine, dihydroetorphine, a few fentanyl analogues etc, and as for myself, I wouldn't go near anything more potent than remifentanyl, and I certainly don't go buggering around with street products based on fentanyl or its analogues "china white" etc. unless perhaps, I had a friend standing over me with a syringe full of naloxone in case the clandestine chemist behind the synth in the first place cocked things up during dilution of the drug.
It is in my opinion, a matter of relative risk, to the possible benefits gained, dropping a few tabs, or vegging out for the day with a shot or two of morphine and an ounce of good green isn't going to do me in, not by a long way, but go out to the wrong sushi bar at the wrong time, and eating the wrong bit of (ugggh) raw fish, just might.
So, keep your poisonous raw fish, you are more than welcome to it