[mytotoro]

I'm doing some dermatology work and I'm wondering if it is possible to make a chemical equivalent of a tewl - perhaps activated through water or another catalyst (under normal conditions, lighting, temp)

If so, what subjects should I be looking into?

Thanks a lot

[Arkcon]

Your tern, TEWL, is medical jargon for a very complex process -- the loss of water through a human organ (human skin, since other animals likely have very different skin dynamics.)  I don't know how you're going to relate that to a chemical system -- reaction vessels don't have human organs.  Or, if you're trying to enhance this process in human skin itself, I don't think its an easy comparison to straight chemicals.

[curiouscat]

I'm doing some dermatology work and I'm wondering if it is possible to make a chemical equivalent of a tewl - perhaps activated through water or another catalyst (under normal conditions, lighting, temp)

What's your objective?

[mytotoro]

What's your objective?

I'm trying to make measuring TEWL more portable and less invasive than carrying something like a VapoMeter

[fledarmus]

There are synthetic membrance models that are being used to predict PK/PD properties (that's pharmacokinetic/pharmacodynamic, not -log K/-log distribution coefficient). You could probably generate similar models with the appropriate porosity to model TEWL.

[mytotoro]

There are synthetic membrance models that are being used to predict PK/PD properties (that's pharmacokinetic/pharmacodynamic, not -log K/-log distribution coefficient). You could probably generate similar models with the appropriate porosity to model TEWL.

Hey fledarmus, I can't send PM's but can you PM me or email me at yk.he @ live.com, I'd like to speak to you personally if possible,

Thanks!