Suggest the relative orders of the 4 pKa values between cis-butanedioic acid and trans-butanedioic acid. i.e. each of the isomers can dissociate twice; of the therefore 4 acidic protons, they must be ranked in terms of acidity.
How do I go about this? Which makes it easier to dissociate, cis or trans, for each of the protons?