November 23, 2024, 07:53:07 PM
Forum Rules: Read This Before Posting


Topic: Optimizing reaction conditions: temperature, pH, etc.  (Read 1679 times)

0 Members and 2 Guests are viewing this topic.

Offline ajohnson388

  • Very New Member
  • *
  • Posts: 1
  • Mole Snacks: +0/-0
Optimizing reaction conditions: temperature, pH, etc.
« on: March 30, 2014, 05:40:05 PM »
Hi,

I am about to finish my second semester of organic chemistry, but have still yet to learn how to derive reactions conditions for syntheses. I was wondering if anyone can lead me in the right direction, via books, links, or keywords, so i can learn more on how to derive the best pH, temperature, and pressure values for any synthesis. Surprisingly, I am having a great deal of trouble finding this information, so any pointers would be great. Also, I am not looking for qualitative information such as heat or no heat, but actual values that can be predicted or close to it.

Thanks,
Andrew

Offline discodermolide

  • Chemist
  • Sr. Member
  • *
  • Posts: 5038
  • Mole Snacks: +405/-70
  • Gender: Male
    • My research history
Re: Optimizing reaction conditions: temperature, pH, etc.
« Reply #1 on: March 30, 2014, 09:13:17 PM »
No hard and fast rules, just lots of experience. Also lots of literature experimental procedures one can follow.
Chemistry is an experimental science.
Development Chemists do it on Scale, Research Chemists just do it!
My Research History

Offline orgopete

  • Chemist
  • Sr. Member
  • *
  • Posts: 2636
  • Mole Snacks: +213/-71
    • Curved Arrow Press
Re: Optimizing reaction conditions: temperature, pH, etc.
« Reply #2 on: March 31, 2014, 10:12:21 AM »
I agree with Disco. One of my favorite places to start is with Organic Synthesis. It is very useful to read the notes here as well.
Author of a multi-tiered example based workbook for learning organic chemistry mechanisms.

Sponsored Links