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Topic: Using DCC when acid is not very soluble  (Read 1450 times)

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Offline millsware

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Using DCC when acid is not very soluble
« on: April 01, 2014, 10:31:39 AM »
Can you use DCC to activate a carboxylic acid if the starting acid is not very soluble in organic solvents?  I imagine that as the active ester is formed it will go into solution.
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Offline Babcock_Hall

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Re: Using DCC when acid is not very soluble
« Reply #1 on: April 01, 2014, 01:02:34 PM »
When I have an acid that is not very soluble, I use a lower concentration of the acid than I otherwise would.  Can you provide more details about your starting material and product.
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