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Topic: Predicting the major product  (Read 2268 times)

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Offline miked87

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Predicting the major product
« on: November 27, 2014, 05:44:17 PM »
Hi all,

Unfortunately organic chemistry isn't my strong point (love inorganic and physical) I always struggle with it.. Due to a bereavement I have slipped behind and I don't even know where to begin on this question? Can any one give me any advice? Help? Anything? Thank you in advance

Offline Arkcon

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Re: Predicting the major product
« Reply #1 on: November 27, 2014, 06:38:27 PM »
Do you know what class of compound the second reagent is?  If you know the general class, do you know, or can you look up online and in a textbook, what reactions it undergoes?  These are good ways to start, when you've fallen behind.

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Offline OrgXemProf

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Re: Predicting the major product
« Reply #2 on: November 27, 2014, 11:17:12 PM »
Another aspect of the indicated reaction should be considered: Note that the first compound contains a chiral center (only the S-enantiomer is shown).

Thus, after you have decided the manner in which the second compound reacts with the first, the question of reaction diastereoselectivity with concomitant asymmetric induction that accompanies erythro vs. threo product formation should be considered.

The following reference may prove helpful: http://en.wikipedia.org/wiki/Asymmetric_induction


Offline miked87

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Re: Predicting the major product
« Reply #3 on: December 19, 2014, 08:38:00 AM »
Hello all.... thanks for your help

I have tried my hardest with this and this is what I have come up with, can someone check if I have tackled it correctly?

Cheers


Offline Mellitic

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Re: Predicting the major product
« Reply #4 on: December 19, 2014, 01:59:09 PM »
So what is the stereochemistry of your new alcohol?

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