[subro]

Hello, I have a question about which is the best way for synthesize an stereoselectively E alkene. The two options that I'm comparing are Julia olefination (well, Kociensky mod. because it's simpler) or Schlosser Mod. (Wittig with lithium salts). I dont know with which way I will have more stereoselectivity.

Any idea?

Thanks in advance.

[pgk]

Try the stereoselective Witting. Might be a lower yield but the base preparation, overall operation and purification are simple. However, the stereoselectivity of the Witting reaction depends on the stucture of the Witting reagent (See the literature).