[jiangzheng248]

hi,
we do the medical product container extractable study, and we found sulfur (mg/mL) in extractable by ICP-MS.  We know the parent compound was element sulfur in the container. I just want to know after this tiny quentity of sulfur leach form container and undergo at least 121 degree 20 min Autoclave in the air, what the final formation about this sulful. I guess it will be sulfate, but without any sicentific evidence.

[Arkcon]

If you need to know the particular ionic form of the sulfur, then maybe you can see it by ion chromatography.  This really depends on how much you can extract, but ion chromatography can be nearly as sensitive as ICP.

[jiangzheng248]

HI,
THx for the suggestion.
As the extractaion solution was phosphate buffer and sulfur level was very low. so we donot think that  ion chromatography will work. Actually ,we talked about using Capillary electrophoresis CE-ICP-MS techniques to separate different ionic sulfur single. We send samples to aglient co., but the conc. was too low and cannot be detected. So we back to searach is there any relevent literature about sulfur formation after autoclave.
thx