November 17, 2024, 02:42:51 AM
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Topic: Bulky base in elimination reaction  (Read 2157 times)

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Offline gg66

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Bulky base in elimination reaction
« on: December 16, 2015, 05:41:23 PM »
Can someone please explain why the answer is A in this picture attached in the link? I would have thought that it would prefer to make 1-hexene because a bulky base is being used, and thus needs to go to the least hindered hydrogen?

http://puu.sh/lY60q/2c5adaf982.png

Offline Babcock_Hall

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Re: Bulky base in elimination reaction
« Reply #1 on: December 17, 2015, 09:35:05 AM »
Which answer do you think is better?

Offline Vidya

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Re: Bulky base in elimination reaction
« Reply #2 on: December 17, 2015, 10:03:49 AM »
Do you know any thing about Hofmann product and zaitsav s product ?
Do you think that the given substrate and base in A option are in favor of Hofmann product?

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