[HELP!]

Does anyone have any tips on how to study for the ACS Biochemistry exam???

[Mitch]

See point 7.

http://www.chemicalforums.com/index.php?topic=3190.0

[fleazo]

I checked the point 7 and it is not just easy to buy past exams.  They need to verify you are an educator so you might be out of luck especially on short notice. 

just got out of the 2007 ACS biochem exam.  I believe its the same one that is being used all through 2008.



I was told I took the 1 semester exam, but the questions were similar to what has been described, so maybe these exams are the same.  My biochem course was 1 semester and this exam was supposedly the 1 semester exam.  I believe this because there were no questions on the urea cycle or photosynthesis



for the 1 semester exam, it was not hard, it was not easy. It was medium.  I had to self teach myself biochemistry, I mean the entire semester, and taught myself from a lippincott book and I feel I wasn't totally prepared.



Anyway, questions



Know glycolysis thoroughly, the enzymes involved.  Which steps produce NADH. 

What pathways and enzymes does ATP inhibit?

What is the use of the NADPH produced in HMP?  Is it used in anabolic or catabolic reactions?

Recognize the STRUCTURES (not the functions) of biotin, TTP, THP, PPT?  I wasn't sure what PPT was.  You need to destinguish between them

Know the difference between competitive and non-competitive inhibitors and their effects on graphs

Know what is on the coordinates of the enzyme graphs that measure Km, Vmax

Know SDS-Page

Know PCR

If you are given a 4 small polypeptides amino acids (like glu-his-gly-arg), be able to recognize at a given pH the order those polypeptides will migrate to anode/cathode.  Memorize your pkas! 

BTW the one letter codes and three letter codes are given on the exam

Know how much ATP is produced from Kerb's and know where it is produced at (which steps)

Know in glycolysis and Kreb's cycle where NADH, FADH2, etc are produced

What is the difference between glycolysis and gluconeogenesis?  (throroughly know difference in terms of structure, enzymes, etc)

Know translation in the sense, what will a point mutation do to amino acid sequence?  What will a deletion do?  Etc.

Whats the differences between bacterial and eukaryotic DNA replication?

Know translation, what are promoters, etc?

What are the enzymes in the pyruvate dehydrogenase complex?

What are the end products of the Kerb's cycle ONLY?

In globular proteins, what might be used to break cys redisues?  If you know, know a lot about that answer!

In hemoglobin, know generally how O binds, what does 2,3BPG what about the differences in going from the T to the R state?

Know the basic difference between an anabolic and catabolic pathway (which is reductive, oxidative?)

Whats a thioester bond?

Which lipids have glycosidic linkages? 

What are the allosteric effectors of the steps in the Kreb's cycle?



OK guys thats about what I remember for now.  If anyone has more questions just post them i will check in every once and a while



I am just trying to give a study guide here because there isn't one.  There is more than just this stuff, and every thing I mentioned know it thoroughly!  The questions are asked in a way that you should understand it just not have things memorized! 



Hope this helps!