September 28, 2024, 11:30:40 AM
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Topic: Retrosynthetic analysis  (Read 6024 times)

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Offline Babcock_Hall

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Re: Retrosynthetic analysis
« Reply #15 on: March 08, 2016, 09:31:32 AM »
What is the product of an acyl chloride and an amine?  How else can you give a carbon a partial positive charge?

Offline kriggy

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Re: Retrosynthetic analysis
« Reply #16 on: March 08, 2016, 09:50:32 AM »
An acyl chloride?

Can you draw the reaction scheme? It seems that you are just guessing

Offline zarhym

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Re: Retrosynthetic analysis
« Reply #17 on: March 09, 2016, 02:00:57 AM »
There are many ways to synthesis your target molecule. The more tools you have, the easier it will be.

Offline Alwin Kristen

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Re: Retrosynthetic analysis
« Reply #18 on: March 24, 2016, 03:30:51 AM »
It's been awhile since this thread has been active so I thought this suggestion for retrosynthetic pathway could come handy for who ever it needed.

To do retrosynthesis you need to know your reactions. A book of named reactions or a database of reactions is the best friend of chemist who does retrosyntheses. In retrosynthetic analysis there is no straight answer of how to do it right for certain molecule. There is so many different ways to do it as there is chemists. A realy good book to get familiar with retrosynthesis is Stuart Warren Organic Synthesis: The Disconnection Approach
Also I would recommend a book from E. J. Corey: The locig of chemical synthesis. It is a little bit more advance than book from Warren.
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