Not quite. 1,2 are enantiomers because the lower stereo center has 2 identical groups attached. 3,4 are enantiomers. step 1) Assign R,S config. step 2) Did all of the symbols flip? Yes:enantiomers No: diastereomers. For many, it's easier to think in terms of R's and S's than in 3 dimensions.